Maude’s death came out of nowhere in season 11 in a darkly humorous way and was the result of a pay dispute with her voice actress. ‘At first they thought it must be a mistake. For example, if all of a sudden we notice that the incidence of ITP rises to 6 or 9 per 100,000 adults/year after getting a vaccine, then that would be a signal that there could be a problem. Dr. Nick's revival isn't an isolated case in The Simpsons. The Simpsons has killed off a few characters over the years, including Dr. Nick, the world's worst physician, but the writers soon brought him back. Remember when she said she has always been a little anaemic. Three turned out to be exacerbations of preexisting ITP and were excluded, but the review also reported one fatality due to intracranial hemorrhage, the same complication that took Dr. Michael’s life. He will join Maude Flanders, Bleeding Gums Murphy, Mona Simpson (Homer’s mom), Amber Simpson (Homer’s Las Vegas wife), and Edna Krabappel in the Springfield graveyard. Given that there were approximately 44,000 subjects in the Pfizer/BioNTech trial with not a single patient showing signs if ITP, we can reasonably conclude that, even if the Pfizer/BioNTech vaccine increases the risk of ITP or causes ITP, the risk must be very, very low. Given that there are over 200 million adults in the US, this would lead to an estimate of around 16 adults per day being diagnosed with ITP. That means that, in any given three day period (chosen because Dr. Michael’s wife reported that her husband’s symptoms began three days after he was vaccinated with the Pfizer/BioNTech COVID vaccine), one would expect approximately 48 adults to be diagnosed with ITP. Given how low the annual incidence of ITP is at baseline taken in context with the fact that there will be tens of millions of adults vaccinated with the Pfizer/BioNTech vaccine this year, we would expect to see a significant increase in the annual incidence of ITP if this vaccine did actually increase the risk of ITP. Comments Add a Comment. As bad as I feel for her, I just wish that Ms. Neckelmann hadn’t in her grief leapt to the conclusion that it was definitely the COVID-19 vaccine that had caused her husband’s death from ITP and trumpeted his story as a warning to the world, so that his death wouldn’t be “in vain.” Her Facebook post handed the antivaccine movement and COVID-19 cranks a powerful propaganda weapon. The most common symptoms of ITP include, of course, the petechiae and purpura mentioned before (small lesions on the skin due to bleeding under the skin), plus any or all of the following: There are a number of conditions that have been associated with the development of ITP: Also, medications can increase the risk of ITP: The treatments for ITP depend upon the type and severity. Murphy is voiced by Ron Taylor, possibly the first guest star in the series if not the first. It was also noted that severe bleeding due to ITP after COVID-19 infection was rare and that diagnosing ITP in the setting of COVID-19 infection is challenging due to the common incidence of clotting disorders and diffuse intravascular coagulation (DIC), which can also cause platelet depletion. (More on the general risk of ITP after vaccination later.). Ron Taylor. The problem then becomes determining whether his tragic outcome was a coincidence or due to the vaccine. Nevertheless, The Simpsons has made the bold decision to kill off a few characters for good over the years. I was taking him to the vet today. Other characters have been retired under tragic real-life circumstances, such as Edna Krabappel, who was retired after the passing of voice actress, Marcia Wallace, in 2013. Bleeding Gums Murphy. Bleeding Gums, Weight Loss. Dr. Gregory Michael, 56, an OB-GYN at Mount Sinai Medical Center in Miami Beach, died after suffering a hemorrhagic stroke apparently resulting from a lack of platelets. A few media reports likely aren’t though. Bleeding Gums died in 1995 at the age of 59 after suffering an apparent heart attack. The world of The Simpsons is one that very much plays by its own rules, with main characters who not only wear the same clothes each day, but also haven't aged since the series began in 1989. Following this, his only album "Sax on the Beach" jumps in price and Lisa plays a tribute to him. Ultimately, Dr. Michael was diagnosed with ITP, and here’s what ultimately happened: After two weeks of infusions and experimental treatments that failed to raise Gregory’s platelet count, doctors decided they had no choice. The Simpsons' showrunner, Al Jean, has since revealed that the falling chunk of glass in the Simpsons movie only knocked Dr. Nick out, and he went on to make a full recovery after the events of "Trappuccino.". Bart, meanwhile, sues Krusty the Clown and is given a $100,000 settlement. Chronic ITP varies from person to person and can last for many years. The 28-year-old DJ died due to massive blood loss from a self-inflicted wound, according to a report from TMZ, quoting 'sources privy to specific information about Avicii's death'. True, ITP is listed on the Gardasil package insert as a possible adverse reaction, but, as Dr. Iannelli goes on to explain further, later studies have shown no association, and the risk of getting ITP after an actual measles infection is considerably higher than the risk of ITP after the MMR vaccine, thus leading him to point out that “worry about ITP is a not a good reason to skip or delay getting vaccinated”. And when you think of Jazz, you have to think of the Jazzman, none other than the late great Bleeding Gums Murphy. It's a common and mild form of gum disease, and it's caused by a buildup of plaque at your gumline. However he died from a hemorrhagic stroke – when blood from an artery bleeds into the brain – before he could undergo the surgery. But they said you cannot go home, this is incredibly dangerous, you could suffer a brain bleed and die.’. :-( JasonOfOrillia. Craig has previously been published on sites such as Den of Geek, and after many coffee-drenched hours hunched over a laptop, part-time evening work eventually turned into a full-time career covering everything from the zombie apocalypse to the Starship Enterprise via the TARDIS. The Simpsons looked to have killed Dr. Nick in the 2007 movie, but couldn't resist bringing the inept physician back to the TV show. (And did you know that the latter even had a name ?) He was married to Deborah Sharpe-Taylor. Another aspect of ITP is that it is usually not life-threatening. If you are a potential patient and found this page through a Google search, please check out Dr. Gorski's biographical information, disclaimers regarding his writings, and notice to patients here. He died of a heart attack aged 49, on January 16, 2002, at his home in Los Angeles, California. Occasional bleeding of the gums can … And, again, this was observed in children, not adults. More: The Simpsons: Ned Flanders Church Plot Hole Explained. Treatment may not be needed. Surgeons were understandably reluctant to operate on a patient whose platelet count was so low as to be almost undetectable, given the extreme risk of bleeding. This Sunday's episode, "Sweets And Sour Marge" is dedicated to the memory of Ron Taylor, who was the voice of Bleeding Gums Murphy. Again, as I said before, “idiopathic” means basically “we don’t know what causes it.” There are also two forms of ITP, acute and chronic, with the acute form occurring mainly in children and the chronic form occurring in adults: Acute ITP generally lasts less than 6 months. Click the button below to start this article in quick view. Unfortunately, Dr. Michael’s case is, at present, a single anecdote, making it impossible to demonstrate causation. I also have another prediction. The go-to source for comic book and superhero movie fans. His funeral took place on January 28 at the New Christ Memorial Church of God in Christ. Yeah you heard it right!! Having previously written for various sports and music outlets, Craig's interest soon turned to TV and film, where a steady upbringing of science fiction and comic books finally came into its own. In mild cases, treatment may not be needed. In cases of refractory ITP, thrombopoietin receptor agonists (drugs that stimulate the receptor) can stimulate the bone marrow to make more platelets. It originally aired on the Fox network in the United States on April 30, 1995. However, some teenagers and children do get this type of ITP. The study cited in the USA TODAY story estimated the attributable risk of developing ITP after MMR vaccination to be 1 in 25,000 vaccinations, which strikes me as rather high. 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Splenectomy can result in durable remission of ITP in up to 80% of patients, but, again, it’s generally risky because of the elevated risk of bleeding in the sorts of patients for whom the operation is generally reserved, namely those with refractory severe ITP. "'Round Springfield" is the 22nd episode of the sixth season.All rights belong to Fox. Taylor's other roles included guest spots in NYPD Blue, Twin Peaks, City of Angels and Star Trek: Deep Space Nine .He died in 2002 aged 49 from a heart attack. Be that as it may, Ms. Neckelman’s post led to sensationalistic headlines, like this one from (who else?) She has lost weight and only drinks water. Certainly, the clinical trials for neither the Pfizer/BioNTech nor the Moderna COVID-19 vaccines detected any signal for ITP in the form of bleeding, low platelet counts, or the like within two months of vaccination. He didn’t smoke, he drank alcohol once in a while but only socially. All the latest gaming news, game reviews and trailers. Unsurprisingly, in her grief she blamed the vaccine for her husband’s death from a rare autoimmune condition that destroys platelets and causes bleeding. Last week, a post by Heidi Neckelmann, the wife of Miami obstetrician Dr. Gregory Michael describing his death from idiopathic thrombocytopenic purpura (ITP) 16 days after being vaccinated with the Pfizer/BioNTech COVID-19 vaccine went viral. He would not eat for (2) days but he was drinking water profusly then throw it up. Learn more about receding gums in this article. With both Dr. Nick and Dr. Monroe returning from apparent death, it could be that The Simpsons' medical experts are so good at their profession, they have hidden powers of regeneration. Ron Taylor, Actor: Trading Places. With Dan Castellaneta, Julie Kavner, Nancy Cartwright, Yeardley Smith. When Bart and Homer destroy the giant glass dome covering Springfield, a large shard of the broken shell falls to the ground and impales Dr. Nick right through the road. Two of the most famous examples include Maude Flanders' darkly comedic death at a sports game, indirectly caused by Homer, and the demise of Bleeding Gums Murphy, Lisa's jazz inspiration. ‘In my mind his death was 100 percent linked to the vaccine. Despite being a reliable source of gags, the 2007 Simpsons movie appeared to kill off Dr. Nick. For more on how, when studying adverse events after vaccination, scientists differentiate coincidence from actual association that might be causal, here’s a good primer. Then he bled to death between midnight an five this morning. What the story means by “had no choice” was the surgical treatment of ITP, namely splenectomy, or removal of the spleen. Near the end of the show, Murphy, from the heavens above, plays this song with Lisa, before he hits his final resting place. 7 | Which of Sunday’s surprise returns did you appreciate more: The Simpsons‘ Bleeding Gums Murphy or Family Guy‘s Holden Caulfield? Chronic ITP lasts 6 months or longer and mostly affects adults. "Round Springfield" is the episode in which "Bleeding Gums" Murphy dies of kidney failure. The reason that splenectomy works is because platelets with antibodies bound to them are taken up by macrophages in the spleen. A one-stop shop for all things video games. If the severity of the injury wasn't enough (this is The Simpsons, after all) Nick delivers a twist on his famous line - "Bye, everybody!" Humans are, as I like to say, pattern-seeking creatures. It’s called “idiopathic” because its causes are unknown or not well understood. In case of emergency, platelet transfusions are used, but this is usually not the first choice because the new platelets are usually chewed up by the autoimmune response just as fast as the patient’s own platelets. How they died: After accidentally being boiled alive by his loving owner, Homer. The first such story has started circulating in the antivaccine nooks and crannies of social media, but it’s also being flogged by the usual British tabloids. Ron Taylor was born on October 16, 1952 in Galveston, Texas, USA as Ronald James Taylor. Show. ‘He felt 100 percent, he was normal, energetic, happy. Even in the case that there is such an association, we know that, for the phase 3 clinical trial to have missed it, the incidence of post-COVID vaccination ITP must be very, very low. Exploring issues and controversies in the relationship between science and medicine. (As I like to say, “idiopathic” basically means “we don’t know the cause.”), The story further noted that ITP is rare and that in extremely rare cases, the measles, mumps and rubella (MMR) vaccine has been linked to thrombocytopenia in children, according to a 2003 study. This seemed to confirm that the character had been written out of the series. ‘They tested him for everything you can imagine afterwards, even cancer, and there was absolutely nothing else wrong with him.’. However, many dental treatments can help restore the gums around the teeth. I used the specific examples of syncope and Bell’s palsy, the former of which is a common reaction to needlesticks of many kinds (including all vaccinations) and the latter of which was almost certainly not related to vaccination against COVID-19, also explaining how the law of large numbers will mean that there will certainly be a lot of health issues manifesting themselves sometime soon after vaccination just by coincidence alone, up to and including death. Watching Dr. Monroe's "accident" in The Simpsons movie again, it certainly seems that the intention at the time was for Dr. Nick to be killed, but his surprise return doesn't negatively impact the show's approach to death. I believe this show was about the death of Lisas favorite sax player, "Bleeding Gums Murphy". 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Dr. Nick returns in "Lost Verizon" and then had a bigger role in "Eeny Teeny Maya Moe," when Moe is looking to get surgery to make himself shorter and taps up Riviera to conduct the operation. Filmography Films The Daily Mail story, as sensationalistic as it is, does provide us with more information that Ms. Neckelmann’s Facebook post: Dad-of-one Gregory suffered no immediate reaction to the injection but three days later he was taking a shower and noticed petechiae – spots of red that indicate bleeding beneath the skin – on his feet and hands. Jim Carrey is Craig’s top acting pick and favorite topics include superheroes, anime and the unrecognized genius of the High School Musical trilogy. They gave him an incredible amount of platelet infusions, I’m told all the platelets in Miami Dade County,’ Heidi said. Dr. Michael apparently died before he could be operated on, as risky as surgery would be. Her post is already doing damage to efforts to persuade people to accept COVID-19 vaccines, as antivaccine groups gleefully spread this story far and wide. Elsewhere, I predicted: The point is that there will be all sorts of scary stories about COVID-19 vaccines in the coming weeks and months, and a lot of people will have reactions similar to mine. As I mentioned above, ITP is an autoimmune condition that results in platelet destruction in the spleen. It’s a thing with a lot of Simpsons characters. Since then, Dr. Nick has resumed his status as a recurring Simpsons character, last appearing in a late 2019 episode of season 31. call and response catchphrase. Unsurprisingly, the first line of treatment, however, is corticosteroids, ranging from oral prednisone in less severe cases to intravenous dexamethasone or methylprednisolone in more severe cases in which the platelet count is so low as to risk bleeding. A Florida doctor has died several weeks after receiving a COVID-19 vaccine, although it’s not yet clear whether his death Monday was related to the shot he received on Dec. 18. Miami medical examiners are investigating his death, the Florida Department of Health said in a statement. So they did the test again and this time did a manual count which is supposed to be more accurate. TV Show: The Simpsons Franchise: Simpsons. Here’s the first story of a death after vaccination against COVID-19 that sounds plausible on the surface that allows me to revisit this issue because, unlike the cases of people who are, for example, hit by a car within two weeks of vaccination, we can’t just dismiss it a priori: A Florida doctor has died several weeks after receiving a COVID-19 vaccine, although it’s not yet clear whether his death Monday was related to the shot he received on Dec. 18. ‘But no matter what they did, nothing helped. Bleeding Gums Murphy's Death + Lisa's and Murphy's final duo. Voiced by Hank Azaria, Dr. Nick Riviera debuted in The Simpsons' second season as a hilariously under-qualified medical practitioner looking to treat Bart after being run over. Bleeding Gums Murphy VOICE. Chronic ITP affects women two to three times more often than men. Look for antivaxxers to spin these coincidences as “definite proof” that the COVID-19 vaccine kills, just the way they’ve done for vaccines and sudden infant death syndrome (which is not caused by vaccines) and for the HPV vaccine and deaths of teenaged girls. Indeed, one of the deaths in the placebo group for the Pfizer vaccine was due to a hemorrhagic stroke. What might lead scientists to think that there is an actual association between vaccination with the Pfizer/BioNTech COVID vaccine and ITP? Unfortunately, pouring gasoline on the flame was, in her understandable grief, Dr. Michael’s wife Heidi Neckelmann, who wrote a Facebook post that rapidly went viral, particularly in antivaccine circles: The love of my life, my husband Gregory Michael MD an Obstetrician that had his office in Mount Sinai Medical Center in…, Posted by Heidi Neckelmann on Tuesday, January 5, 2021. It’s also entirely understandable that Heidi Neckelmann would believe that it was the COVID-19 vaccine that killed her husband. I can only try to imagine what she is going through now, particularly given that her husband was within a couple of years of my age. Be that as it may, another later study noted that bleeding episodes were uncommon among these patients, that the ITP associated with MMR disappeared within a month in 74% patients and only persisted beyond 6 months in only 10%. Returning to the hospital the next day, Lisa becomes sad to learn that Bleeding Gums has died. His real name has never been mentioned; Murphy claims his nickname came from the fact he had never once been to a dentist. “The CDC and FDA are responsible for reviewing COVID-19 vaccine safety data and presenting that information for federal recommendations on vaccine administration,” communications director Jason Mahon said in an email. I've searched the net looking for information on when and how he died, but I have come up empty other that his credits at the Internet Movie Database". Thus, platelet infusions are generally not used except in emergencies when bleeding is occurring or platelet counts are as low as Dr. Michael’s were. It’s always a pleasure to re-watch episodes of the Best. Ron Taylor is the voice of Bleeding Gums Murphy in The Simpsons. Again, you can’t tell that from just one case, however dramatic and tragic. When rituximab binds to CD20, it causes B-cell death and is used against blood cancers and autoimmune diseases. Bleeding Gums Murphy Bleeding Gums Murphy (voiced by Ron Taylor , Daryl L. Coley and Kevin Michael Richardson ) [26] is a jazz musician, idol, and mentor of Lisa Simpson . Every general surgeon knows about ITP, because it is general surgeons who are called upon to do a splenectomy in patients whose ITP is refractory to other treatments. It must, however, be acknowledged that it is possible that COVID-19 vaccination might have caused Dr. Michael’s severe ITP. Another treatment includes rituximab (Rituxan), a monoclonal antibody against the protein CD20, which is found on the surface of B-cells. Nick!" With Dr. Nick, however, the "death" was just a brief gag played for laughs, with no wider ramifications for either the story, or the world of The Simpsons. Ever. Bleeding gums are the most common symptom of gum disease. That would imply that, even if there is such an association, it is far safer to get the vaccine than it is to take the risk of catching COVID-19 – and, again, this is just one story. While the Flanders family losing the matriarch of their house is devastating, her character is not the most memorable. But later, in season 15's "Diatribe of a Mad Housewife," Monroe appears out of the blue at Marge Simpson's book signing. When he checked himself into Mount Sinai Medical Center in Miami Beach, the hospital where he works and had the groundbreaking vaccine, medics discovered he was suffering from an acute lack of platelets. It’s thus probably more likely than not that Dr. Michael’s diagnosis so soon after vaccination is a coincidence. The Daily Mail: Heidi Neckelmann says obstetrician Gregory Michael, 56 – her ‘best friend’ and partner of 28 years – was active, healthy and had no pre-existing conditions before getting the jab on December 18. 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